The 2021 Annual Report to the Nation on the Status of Cancer finds overall cancer death rates continue to decline in the United States for all cancer sites combined. The rapid drop in lung cancer and melanoma deaths led to the overall decline.
A team of international researchers has identified mutations in several genes, including TP53, MYOD1, and CDKN2A, that appear to be associated with an aggressive form of rhabdomyosarcoma in children. The findings could lead to more targeted treatments for the disease.
One study examined whether genetic changes associated with exposure to radiation from the 1986 accident were passed from parent to child. A second study documented the genetic changes in thyroid tumors from people exposed as children or fetuses to radiation from the accident.
A fact sheet about genetic testing for inherited cancer risk, including who should consider testing, how to understand test results, and who has access to a person’s test results. Also contains information about at-home, or direct-to-consumer, genetic tests.