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NCI News Releases
The latest cancer news from the U.S. government's principal agency for cancer research.-
NIH-funded study suggests that testosterone suppresses brain tumor growth in males
In a new National Institutes of Health (NIH)-funded study, scientists at Cleveland Clinic discovered that hormones associated with male development may play a key role in limiting the growth of brain tumors in men. The research team found that the loss of androgen hormones, such as testosterone, in a preclinical model of glioblastoma drove tumor growth by inducing local inflammation and triggering the production of stress hormones.
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NIH-funded AI model predicts cancer survival from single-cell tumor data
In a National Institutes of Health (NIH)-funded study, researchers developed a cancer assessment tool that can identify high-risk patients and the tumor cells linked to that risk. The model, called scSurvival, uses a machine learning framework designed to analyze large-scale data at single-cell resolution.
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Chronic inflammation leaves long-lasting impression on gut stem cells, increasing colorectal cancer risk
In a new study, funded in part by the National Institutes of Health (NIH), researchers have uncovered a molecular mechanism that could explain how chronic gut inflammation may increase the risk of colorectal cancer. By simulating chronic colitis in mice and tracking the colon’s response during inflammation and recovery, scientists demonstrated that these changes increased the activity of a specific group of proteins, AP-1 transcription factors, and promoted tumor growth.
